A Parametric Approach for Classification of Distortions in Pathological Voices

In biomedical acoustics, distortion in voice signals, commonly present during acquisition and transmission, adversely affects acoustic features extracted from pathological voice. Information on the type of distortion can help in compensating for its effects. This paper proposes a new approach to detecting four major types of commonly encountered distortion in remote analysis of pathological voice, namely background noise, reverberation, clipping and coding. In this approach, by applying factor analysis to Gaussian mixture model mean supervectors, distortions in variable-duration recordings are modeled by fixed-length, low-dimensional channel vectors. Then, linear discriminant analysis (LDA) is used to remove the remaining nuisance effects in the channel vectors. Finally, two different classifiers, namely support vector machines and probabilistic LDA classify the different types of distortion. Experimental results obtained using Parkinson's voices, as an example of pathological voice, show 11.4% relative improvement in performance over systems which directly use acoustic features for distortion classification

Quality Control in Remote Speech Data Collection

There is a need for algorithms that can automatically control the quality of the remotely collected speech databases by detecting potential outliers, which deserve further investigation. In this paper, a simple and effective approach for identification of outliers in a speech database is proposed. Using the deterministic minimum covariance determinant (DetMCD) algorithm to estimate the mean and covariance of the speech data in the mel-frequency cepstral domain, this approach identifies potential outliers based on the statistical distance of the observations in the feature space from the central location of the data that are larger than a predefined threshold. DetMCD is a computationally efficient algorithm, which provides a highly robust estimate of the mean and covariance of multivariate data even when 50% of the data are outliers. Experimental results using eight different speech databases with manually inserted outliers show the effectiveness of the proposed method for outlier detection in speech databases. Moreover, applying the proposed method to a remotely collected Parkinson's voice database shows that the outliers that are part of the database are detected with 97.4% accuracy, resulting in a significant decrease in the effort required for manually controlling the quality of the database

A Supervised Approach to Global Signal-to-Noise Ratio Estimation for Whispered and Pathological Voices

The presence of background noise in signals adversely affects the performance of many speech-based algorithms. Accurate estimation of signal-to-noise-ratio (SNR), as a measure of noise level in a signal, can help in compensating for noise effects. Most existing SNR estimation methods have been developed for normal speech and might not provide accurate estimation for special speech types such as whispered or disordered voices, particularly, when they are corrupted by non-stationary noises. In this paper, we first investigate the impact of stationary and non-stationary noise on the behavior of mel-frequency cepstral coefficients (MFCCs) extracted from normal, whispered and pathological voices. We demonstrate that, regardless of the speech type, the mean and the covariance of MFCCs are predictably modified by additive noise and the amount of change is related to the noise level. Then, we propose a new supervised method for SNR estimation which is based on a regression model trained on MFCCs of the noisy signals. Experimental results show that the proposed approach provides accurate estimation and consistent performance for various speech types under different noise conditions

Dominant distortion classification for pre-processing of vowels in remote biomedical voice analysis

Advances in speech signal analysis facilitate the development of techniques for remote biomedical voice assessment. However, the performance of these techniques is affected by noise and distortion in signals. In this paper, we focus on the vowel /a/ as the most widely-used voice signal for pathological voice assessments and investigate the impact of four major types of distortion that are commonly present during recording or transmission in voice analysis, namely: background noise, reverberation, clipping and compression, on Mel-frequency cepstral coefficients (MFCCs) - the most widely-used features in biomedical voice analysis. Then, we propose a new distortion classification approach to detect the most dominant distortion in such voice signals. The proposed method involves MFCCs as frame-level features and a support vector machine as classifier to detect the presence and type of distortion in frames of a given voice signal. Experimental results obtained from the healthy and Parkinson's voices show the effectiveness of the proposed approach in distortion detection and classification

Quality Control of Voice Recordings in Remote Parkinson’S Disease Monitoring Using the Infinite Hidden Markov Model

The performance of voice-based systems for remote monitoring of Parkinson’s disease is highly dependent on the degree of adherence of the recordings to the test protocols, which probe for specific symptoms. Identifying segments of the signal that adhere to the protocol assumptions is typically performed manually by experts. This process is costly, time consuming, and often infeasible for large-scale data sets. In this paper, we propose a method to automatically identify the segments of signals that violate the test protocol with a high accuracy. In our approach, the signal is first split into variable duration segments by fitting an infinite hidden Markov model (iHMM) to the frames of the signals in the mel-frequency cepstral domain. The complexity of the iHMM is capable of growing jointly with the data allowing us to infer a potentially large (asymptotically infinite) number of different phenomena segmented into different hidden states. Then, we identify the segments that adhere to the test protocol by applying a multinomial naive Bayes classifier to the state indicators of segments. The experimental results show that even by using a small amount of training data, we can achieve around 96% accuracy in identifying short-term protocol violations with a 0.2 s resolution

Automatic Quality Control and Enhancement for Voice-Based Remote Parkinson’s Disease Detection

The performance of voice-based Parkinson’s disease (PD) detection systems degrades when there is an acoustic mismatch between training and operating conditions caused mainly by degradation in test signals. In this paper, we address this mismatch by considering three types of degradation commonly encountered in remote voice analysis, namely background noise, reverberation and nonlinear distortion, and investigate how these degradations influence the performance of a PD detection system. Given that the specific degradation is known, we explore the effectiveness of a variety of enhancement algorithms in compensating this mismatch and improving the PD detection accuracy. Then, we propose two approaches to automatically control the quality of recordings by identifying the presence and type of short-term and long-term degradations and protocol violations in voice signals. Finally, we experiment with using the proposed quality control methods to inform the choice of enhancement algorithm. Experimental results using the voice recordings of the mPower mobile PD data set under different degradation conditions show the effectiveness of the quality control approaches in selecting an appropriate enhancement method and, consequently, in improving the PD detection accuracy. This study is a step towards the development of a remote PD detection system capable of operating in unseen acoustic environments